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The LEO Science & Tech Hub is a R&D innovation unit of LEO Pharma. We explore cutting-edge science and technology opportunities with relevance to dermatology. By partnering with public and private institutions in the world’s leading life science cluster in Boston, we act as a catalyst to transform early-stage innovations and technologies into solutions that will improve the quality of life for people with skin diseases. LEO Science & Tech Hub was officially inaugurated in September 2016.
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Precision Medicine in Dermatology.

Precision medicine aims at identifying the most suitable treatment for each individual patient.

In order to achieve this we will require a much deeper understanding about the different factors that contribute to the course of disease between patients with the same disease such as:

Environmental. Genetic. Molecular. Environmental. Genetic. Molecular.

Our current research projects aim at developing technologies that should enable us to adress these questions, resulting in solutions that can one day support treatment decisions.

News from the hub

Oct. 2018 24 LEO Science & Tech Hub Partners with Wearifi and Northwestern University to Develop Wearable Device for Dermatology Research

CAMBRIDGE, Mass.–(BUSINESS WIRE)–LEO Science & Tech Hub, the Boston-based R&D innovation unit of LEO Pharma, announced today that they will partner with Wearifi Inc. and the Center for Bio-Integrated Electronics at Northwestern University to investigate the clinical potential of next-generation wearable electronics in dermatology research. Wearifi designs and develops the world’s smallest, battery-free wearable device. The collaboration will evaluate whether the device and miniaturized sensor technology can inform and enhance drug development and treatment regimens by potentially identifying and measuring key disease-associated biomarkers.

Photo Credit: Wearifi Inc. and the Center for Bio-Integrated Electronics, Northwestern University (Photo Business Wire).

“We are excited to be working with LEO Science & Tech Hub on developing next generation wearables that have the potential to enable personalized medicine for patients suffering from inflammatory skin disease. Natural byproducts from skin metabolism represent a powerful opportunity for biomarker discovery that may create new approaches to diagnose disease, predict clinical deteriorations, and track individual treatment responses,” says Steve Xu MD, Medical Director of the Center for Bio-Integrated Electronics and Instructor in the Department of Dermatology at Northwestern University.

“Wearifi’s miniature wireless devices allow for imperceptible and unobtrusive placement practically anywhere on the body and are currently used to monitor heart rate, respiration rate and UV exposure,” says Anthony Banks, Chief Technology Officer for Wearifi Inc. “Partnering with a leading biopharmaceutical company like LEO to leverage this mm-scale sensor technology could potentially open new avenues to advance skin health.”

“Effectively bringing Wearifi products into the dermatology space will be a challenging endeavor, but one that will push boundaries and help us better understand our limits with regards to the relationship between technology and skin health. We have an opportunity in front of us to learn informative new details about our largest organ and potentially yield pioneering results for our industry,” says Troels Marstrand, Chief Data Scientist at LEO Science & Tech Hub. Initial steps will include a proof of concept study in collaboration with dermatologists and engineers at Northwestern University’s Center for Bio-Integrated Electronics and Northwestern University Feinberg School of Medicine’s Department of Dermatology. The teams involved will explore the feasibility of creating a wearable Volatile Organic Compound (VOC) detector for continuous measurement of both external and internal VOCs.

The LEO Science & Tech Hub is recognized for its unique collaborative approach of seeking cutting-edge technology for dermatological applications. Since its launch, the Hub has successfully formed multiple partnerships to explore minimally invasive biomarker technologies, drug delivery devices, advanced imaging systems and remote monitoring methods with leading research institutes and biotechnology companies including MITEpicore BiosystemsThe Karp LabNovopyxis,Elektrofi and The Wellman Center for Photomedicine at Massachusetts General Hospital.

About Wearifi Inc.
Wearifi Inc. is a spinout from the John Rogers’ Laboratory at Northwestern University’s Center for Bio-Integrated electronics. Wearifi Inc. is revolutionizing wearables through miniaturized sensors small enough to fit on fingernails that work completely battery-free. The company has established development partnerships with multinational companies including L’Oreal, and funding from the U.S. Department of Defense and the National Institutes of Health. For more information, please visit www.wearifi.net or email info@wearifi.net.

About Northwestern University’s Center for Bio-Integrated Electronics
The Center for Bio-Integrated Electronics (CBIE) was established in 2016 by Prof. John Rogers as part of the Simpson Querrey Institute for BioNanotechnology. The CBIE supports fundamental, applied and translational biomedical research to develop soft, biocompatible forms of bioelectronics with unique functionality that could fundamentally transform health care. For more information please visit http://bioelectronics.northwestern.edu or email cbie@northwestern.edu.

About LEO Science & Tech Hub
The LEO Science & Tech Hub is an R&D innovation unit of LEO Pharma dedicated to identifying, developing, and funding innovative solutions that improve the lives of people with skin diseases. It was founded in 2016 as a catalyst to transform early-stage innovations into solutions for improving the lives of people with skin diseases. We collaborate, explore cutting-edge ideas and make investments. We are an agile group of scientific experts with an entrepreneurial mindset and a vision of how to give patients control over disease by predicting, diagnosing, and monitoring conditions. The LEO Science & Tech Hub is based in Cambridge, Mass. For more information, please visit www.leo-scitech.com, or connect with us at engage@leo-scitech.com, on Twitter @LEOscitech or LinkedIn www.linkedin.com/company/leo-science-&-tech-hub/

Contacts

LEO Science & Tech Hub
Alex Ignatius Costa
AGXDK@leo-pharma.com
or
Media Contact:
LaVoieHealthScience
Anthony Karamourtopoulos, 617-374-8800 ext. 104
akara@lavoiehealthscience.com
or
Wearifi Inc.
Anthony Banks
abank@mywearifi.com

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Sep. 2018 18 LEO Science & Tech Hub Partners with Epicore Biosystems to Explore Wearable Skin Sensors to Improve Dermatologic Treatment Regimens

LEO Science & Tech Hub, the Boston-based R&D innovation unit of LEO Pharma, has announced a new partnership with Epicore Biosystems focused on exploring the use of a non-invasive, wearable sweat sensor to measure prognostic biomarkers in real time, monitor patient response and inform treatment decisions. The initial project will include a proof of concept study in collaboration with engineers and dermatologists at Northwestern University’s Center for Bio-Integrated Electronics and Feinberg School of Medicine’s Department of Dermatology to establish baseline measurements and milestones to validate the clinical relevance of the approach for patients with atopic dermatitis (eczema).

A central goal of precision medicine is to predict early on if a given treatment will work for the individual patient. As atopic dermatitis (eczema) is a diverse skin disease, not all patients will benefit equally from a given treatment,” says Michael Sierra, VP of the LEO Science & Tech Hub. “The possibility of enabling healthcare professionals to characterize skin hydration and disease-specific biomarker responses in real-time and in turn, helping them provide personalized treatment regimens for patients, is an extremely powerful concept. We believe that wearable technologies will have a major impact on the future of healthcare and LEO is fortunate for the opportunity to contribute our expertise in skin research and drug development to this project.”

“The possibilities for driving targeted therapies based on high throughput and low-cost analysis of biomarkers in sweat are limitless,” said Roozbeh Ghaffari, PhD, co-founder and CEO of Epicore Biosystems. “We’re excited about our partnership with LEO Science and Tech Hub, and see it leading to new classes of wearable metabolic sensors that enable remote tracking of skin disease biomarkers and help accelerate interventions once patients leave the hospital.”

“Sweat is a largely unexplored body fluid when it comes to disease biomarkers. I am excited about this project as it pushes the boundaries of both our technological knowhow and our biological understanding. Our vision, which is to develop an ‘at-home-patch’ test, will give patients the ability, early on, to determine if they benefit from a particular antibody treatment or need to try an alternative,” says Troels Marstrand, Chief Data Scientist LEO Science and Tech Hub.

The LEO Science & Tech Hub is recognized for its unique collaborative approach of seeking cutting-edge technology for dermatological applications. Since its launch, the Hub has successfully formed multiple collaborations to explore minimally invasive biomarker technologies, drug delivery devices, advanced imaging systems and remote monitoring methods with leading research institutes and biotechnology companies including MITThe Karp LabNovopyxisElektrofi and The Wellman Center for Photomedicine at Massachusetts General Hospital.

About Epicore Biosystems

Epicore Biosystems is a spinout company from Prof. John Rogers’ Laboratory at Northwestern University’s Center for Bio-Integrated Electronics. Epicore Biosystems has developed skin-like wearable fluidic sensors that are capable of non-invasively measuring metabolic and digital biomarkers in real-time. The company has established partnerships with Fortune 100 companies, the Department of Defense, and leading research hospitals to drive personalized care with their wearable fluidic products. For more information please visit www.epicorebiosystems.com or email info@epicorebiosystems.com.

About Northwestern University’s Center for Bio-Integrated Electronics

The Center for Bio-Integrated Electronics (CBIE) was established in 2016 by Prof. John Rogers as part of the Simpson Querrey Institute for BioNanotechnology. The CBIE supports fundamental, applied and translational biomedical research to develop soft, biocompatible forms of bioelectronics with unique functionality that could fundamentally transform health care. For more information please visit http://bioelectronics.northwestern.edu or email cbie@northwestern.edu.

About LEO Science & Tech Hub

The LEO Science & Tech Hub is an R&D innovation unit of LEO Pharma dedicated to identifying, developing, and funding innovative solutions that improve the lives of people with skin diseases. It was founded in 2016 as a catalyst to transform early-stage innovations into solutions for improving the lives of people with skin diseases. We collaborate, explore cutting-edge ideas and make investments. We are an agile group of scientific experts with an entrepreneurial mindset and a vision of how to give patients control over disease by predicting, diagnosing, and monitoring conditions. The LEO Science & Tech Hub is based in Cambridge, Mass. For more information, please visit www.leo-scitech.com, or connect with us at engage@leo-scitech.com, on Twitter @LEOscitech or LinkedIn www.linkedin.com/company/leo-science-&-tech-hub/

To read on Businesswire, click on this link. 

Contacts

LEO Science & Tech Hub
Alex Ignatius Costa
AGXDK@leo-pharma.com
or
Media Contact:
LaVoieHealthScience
Anthony Karamourtopoulos, 617-374-8800 ext. 104
akara@lavoiehealthscience.com
or
Epicore Biosystems
Roozbeh Ghaffari
info@epicorebiosystems.com

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Contact

We want to engage with partners that have unique innovative skills to generate solutions that will improve the quality of life of patients with skin disease.

Tel. +1 201 396 1645
michael.sierra@leo-scitech.com
LinkedIn

Michael Sierra Vice President Email me