Who are we?
Precision Medicine in Dermatology.
In order to achieve this we will require a much deeper understanding about the different factors that contribute to the course of disease between patients with the same disease such as:
Environmental. Genetic. Molecular.
Our current research projects aim at developing technologies that should enable us to adress these questions, resulting in solutions that can one day support treatment decisions.
News from the hub
LEO Science & Tech Hub, the Boston-based R&D innovation unit of LEO Pharma, has announced a new partnership with Epicore Biosystems focused on exploring the use of a non-invasive, wearable sweat sensor to measure prognostic biomarkers in real time, monitor patient response and inform treatment decisions. The initial project will include a proof of concept study in collaboration with engineers and dermatologists at Northwestern University’s Center for Bio-Integrated Electronics and Feinberg School of Medicine’s Department of Dermatology to establish baseline measurements and milestones to validate the clinical relevance of the approach for patients with atopic dermatitis (eczema).
A central goal of precision medicine is to predict early on if a given treatment will work for the individual patient. As atopic dermatitis (eczema) is a diverse skin disease, not all patients will benefit equally from a given treatment,” says Michael Sierra, VP of the LEO Science & Tech Hub. “The possibility of enabling healthcare professionals to characterize skin hydration and disease-specific biomarker responses in real-time and in turn, helping them provide personalized treatment regimens for patients, is an extremely powerful concept. We believe that wearable technologies will have a major impact on the future of healthcare and LEO is fortunate for the opportunity to contribute our expertise in skin research and drug development to this project.”
“The possibilities for driving targeted therapies based on high throughput and low-cost analysis of biomarkers in sweat are limitless,” said Roozbeh Ghaffari, PhD, co-founder and CEO of Epicore Biosystems. “We’re excited about our partnership with LEO Science and Tech Hub, and see it leading to new classes of wearable metabolic sensors that enable remote tracking of skin disease biomarkers and help accelerate interventions once patients leave the hospital.”
“Sweat is a largely unexplored body fluid when it comes to disease biomarkers. I am excited about this project as it pushes the boundaries of both our technological knowhow and our biological understanding. Our vision, which is to develop an ‘at-home-patch’ test, will give patients the ability, early on, to determine if they benefit from a particular antibody treatment or need to try an alternative,” says Troels Marstrand, Chief Data Scientist LEO Science and Tech Hub.
The LEO Science & Tech Hub is recognized for its unique collaborative approach of seeking cutting-edge technology for dermatological applications. Since its launch, the Hub has successfully formed multiple collaborations to explore minimally invasive biomarker technologies, drug delivery devices, advanced imaging systems and remote monitoring methods with leading research institutes and biotechnology companies including MIT, The Karp Lab, Novopyxis, Elektrofi and The Wellman Center for Photomedicine at Massachusetts General Hospital.
About Epicore Biosystems
Epicore Biosystems is a spinout company from Prof. John Rogers’ Laboratory at Northwestern University’s Center for Bio-Integrated Electronics. Epicore Biosystems has developed skin-like wearable fluidic sensors that are capable of non-invasively measuring metabolic and digital biomarkers in real-time. The company has established partnerships with Fortune 100 companies, the Department of Defense, and leading research hospitals to drive personalized care with their wearable fluidic products. For more information please visit www.epicorebiosystems.com or email email@example.com.
About Northwestern University’s Center for Bio-Integrated Electronics
The Center for Bio-Integrated Electronics (CBIE) was established in 2016 by Prof. John Rogers as part of the Simpson Querrey Institute for BioNanotechnology. The CBIE supports fundamental, applied and translational biomedical research to develop soft, biocompatible forms of bioelectronics with unique functionality that could fundamentally transform health care. For more information please visit http://bioelectronics.northwestern.edu or email firstname.lastname@example.org.
About LEO Science & Tech Hub
The LEO Science & Tech Hub is an R&D innovation unit of LEO Pharma dedicated to identifying, developing, and funding innovative solutions that improve the lives of people with skin diseases. It was founded in 2016 as a catalyst to transform early-stage innovations into solutions for improving the lives of people with skin diseases. We collaborate, explore cutting-edge ideas and make investments. We are an agile group of scientific experts with an entrepreneurial mindset and a vision of how to give patients control over disease by predicting, diagnosing, and monitoring conditions. The LEO Science & Tech Hub is based in Cambridge, Mass. For more information, please visit www.leo-scitech.com, or connect with us at email@example.com, on Twitter @LEOscitech or LinkedIn www.linkedin.com/company/leo-science-&-tech-hub/
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Innovation isn’t easy. Establishing the framework for your corporate innovation unit is the first step in the process, but how can you ensure its success from there?
At LEO Science & Tech Hub, we believe you are only as good as the team around you. We believe that one of the foundations for driving innovation in any organization is competent teams but lately we have been asked again and again “how do we hire or find innovative individuals?”. Here are some insights from us on how to build a team that can solve complex problems, challenge the status-quo and drive innovation forward:
- Environment sets the tone and creates the culture:
Innovation is a mindset – it is a way of thinking and behaving. We do not hire innovative employees, we bring talented and committed individuals into an innovative environment. We maintain this environment by consistently reinforcing our mission and encouraging an experimental culture that values every team member’s ideas and input.
It’s important to set the stage for this type of workplace by developing infrastructure and best practices that are in line with your vision and that support the culture you want to create and foster. This objective provides a platform that will help enable innovative performance from your team on a day-to-day basis and over the long term rather than it just being a buzzword.
- Diverse teams solve problems:
The more diverse your team, the better. This is true especially when thinking about the goal of driving innovative projects forward. A team that consists of subject matter experts across a broad range of fields brings balance and versatility to your group, which will make you more prepared to address different challenges as they arise. Some team members may be market experts, while others are researchers, engineers, strategists, etc. Some may be analytically-minded while others are creative thinkers. Acknowledge these differences and more importantly, capitalize on the ways in which they can complement each other. Promote the internal exchange of knowledge, perspectives and networks. Lean on certain personnel when their skill set aligns closely with a specific project. This type of synergy amongst a diverse group can help each individual form new connections and can ultimately trigger new ideas.
- Team dynamics:
Capabilities and team dynamics go hand in hand. The capabilities of the team members affect how the team addresses problems and identifies solutions, thus creating a unique team dynamic. Changing a team member changes the team dynamics and hence recreating the dynamics is essential to driving innovation.
Our team functions like a commando-like team where we are able to support and move forward even if one of the team members is absent or leaves the team. Teams need to find the right balance for not only having the depth of expertise but also the breadth – they are able to cover a wide range of expertise. It is achieved by building a strong team foundation very early on. This ensures each individual embraces their own capabilities while trusting the capabilities of their teammates and understanding that together they can create successes.
- Bigger isn’t always better:
Our team is small, flat and agile with no hierarchy – everyone knows their role. Keeping a team small ensures that communication is always aligned, decisions are made quickly, and priorities are clear and focused on deliverables. Again, everyone’s questions, insights and perspectives are encouraged, which we believe naturally fuels progression and creates trust. The size of our team inspires cooperation, but also gives each member a sense of ownership, autonomy and accountability. Work becomes more meaningful when each individual is able to see the positive impact they can have on the growth of the unit.